Showing posts with label RESEARCH. Show all posts
Showing posts with label RESEARCH. Show all posts

4 November 2020 - JACQUES COUSTEAU - AMAZING PIONEER


 JACQUES COUSTEAU
 - AMAZING PIONEER -

G'day folks,

Welcome to one of my heroes. 

Born in 1910 off of the French east coast, the great blue expanses of the ocean which were at the backdrop of his childhood remained a constant in the life of Jacques-Yves Cousteau. The draw of the ocean never relented its hold on Cousteau, and in 1930, he enrolled with the French navy. 

It was during this time, serving on a French battleship, that Cousteau turned dream to action and started conducting his first underwater experiments. It was during the tumultuous war that Cousteau began filming prize-winning underwater documentaries, as well as innovate diving technology in ground breaking ways. The Aqua-Lung, which he helped design, was the first open-circuit, self-contained breathing apparatus ever created.




 Of course, films and underwater excursions weren’t the only things that Cousteau did in those years, and as a member of the French Resistance movement, he took part in several complicated operations to thwart the Nazis and their axis powers, and help the allied armies.

Sadly, during that very same time, his brother Pierre-Antoine was busying himself with far darker endeavors. Pierre-Antoine Cousteau was a writer for the ominously-named "Je Suis Partout" (“I am everywhere”), a fascist magazine with pro-Nazi leanings, which called for the internment of all French Jews. He remained an unrepentant white supremacist until his death of cancer in 1958.

The stark contrast between the two brothers only serves to shine a light on the one-of-a-kind character of Jacques Cousteau.

 After the war, Cousteau helped clear the Mediterranean of mines, using his excursions as an excuse to continue his sea explorations and filming, including the very first unassisted underwater archaeology outing, exploring the wreckage of a Roman vessel off the coast of Tunisia.

It wasn’t just the wrecks that littered the bottom of the sea that caught Cousteau’s attention, as the creatures of the ocean enthralled Cousteau even more, and he was actually the first man who correctly predicted the presence of some kind of echolocation system in cetaceans, like dolphins and porpoises.




But it was in the early 60's that he began advocacy for environmentalism when the French Commission for Atomic Energy set in motion a plan to dump radioactive waste into the Mediterranean. It was only due to his activism that wide protest arose against the CAE’s plan and they were forced to nix it.

 His growing fame as an author and film-maker earned him a slot in television with the eye-opening program "The Undersea World of Jacques Cousteau"(1966-1976), which brought Cousteau’s underwater adventures to every living room.

His one of a kind documentaries were the first and only ones to win the Palme d’Or at Cannes, until 2004 when Michael Moore won one for “Fahrenheit 9/11”.

 It is told that during filming in Cuba, Cousteau met with leader Fidel Castro and befriending him, subsequently talking the dictator into releasing some 80 prisoners.

Perhaps most importantly in his efforts to protect marine environments, in 1990, Cousteau got all major powers to sign a petition banning oil drilling in Antarctica, and we can only shudder, imagining what the condition of the ice shelves of the South Pole would have been like today if it were not for this great pioneer of diving.

 
Clancy's comment: I've probably seen all of his documentaries. What a legend.

I'm ...
 







17 August 2019 - SOME CREEPY ANIMALS MAY SAVE LIVES





SOME CREEPY ANIMALS 
MAY SAVE LIVES

G'day folks,

Wasps, spiders, and cockroaches may be creepy, but all 3 may soon be able to revolutionize medical research. Let’s all admit it, the majority of people have a difficult relationship with most arthropods. 

One of the most common phobias in the world is arachnophobia, the fear of spiders (and other arachnids such as scorpions), so that relationship has gone downhill before it had a chance to start. The story with insects is very similar: we consider a lot of them to be pests, and the rest are just some strange alien creatures that just happen to live on the same planet with us. Little did we know that these creepy-crawlies may hold the key to the medical research of the future.




SPIDERS

Although arachnid research in the field of medicine is still in the developing stages, scientists managed to isolate two main resources (spider venom and spider silk) that could potentially transform the way we treat certain conditions.


Spider venom, in particular, has been tested as an experimental treatment of pain caused by IBS (irritable bowel syndrome), as well as a substance that could potentially treat epileptic seizures.

More specifically, an Australian research team has managed to isolate a protein from the venom of a species of tarantula, Heteroscodra maculata, that can block the pain signals from the intestines to the central nervous system. The researchers then developed a treatment that was shown to inhibit IBS-related pain, at least in animal models. A different Australian research group looked at how a peptide isolated from spider venom can potentially help treat seizures in Dravet’s syndrome, a severe type of epilepsy characterized by an extreme sensitivity to high temperatures. 

Spider silk is the strongest biological material on the planet, not to mention it’s very flexible and light, no wonder researchers are looking at its potential to be used in sutures and bandages, as well as medical devices and prosthetics. A research team based at the University of Massachusetts Lowell promises to come up with a new generation of spider silk-based materials that may soon transform not only medical supplies but also protective and sports equipment.




COCKROACHES

Cockroaches may be a pest in your mind, which they definitely are, but medical science found a use even for these creepy creatures. Some researchers plan on using them as a cheaper alternative to common lab animals, like mice, in some experiments, whereas others claim the cockroach brain may hold the secret to treatment for antibiotic-resistant bacteria.

In fact, in China, there are entire cockroach-breeding farms, as ground-up cockroaches are believed to treat gastrointestinal problems. Also, a research team in the UK found that the brains of cockroaches and locusts contain at least 9 different compounds that could potentially kill drug-resistant bacteria.
 The researchers hope one of these compounds may be the key to a cure for infections caused by such increasingly-resistant bacteria, like Escherichia coli and MRSA.
WASPS

A fear of wasps is completely warranted, as their stings can be not only spontaneous and extremely painful, but also commonly cause allergic reactions. But, as it often happens in medicine, toxic substances may hide a secret medical use that may save lives in the future.

In the case of wasp and hornet venom, there are at least 2 different compounds that may open the door to medical innovation. The most-studied compound is mastoparan, a peptide that can be found in the venom of different species of wasps and hornets. 
Mastoparan has been found to have antimicrobial, antibiotic and even anti-cancer properties, but there is a catch.

It turns out that, while mastoparan does kill the harmful bugs and makes certain tumors vanish, it is toxic to the healthy cells as well, so the next hurdle in clinical research is a more targeted treatment. Finally, a different type of peptides (ampulexins) from the venom of emerald jewel wasps, on the other hand, are currently reviewed as a potential treatment of Parkinson’s disease.

As you can tell, the majority of these research projects are a work in progress, but it’s fun to entertain the idea of these arthropods saving human lives nevertheless. It would be an unexpected turn of events to find yourself in a situation where you owe your health to a creature you despise, wouldn’t it?
Clancy's comment: I'm not surprised at all. Who cares where we find things to repair humans?
I'm ...